Working at night increases the risk of cancer according to MIT study.
Working at night is not good for health. The alterations of the sleep-wake cycle have long-term negative effects on the workers' organism, as a greater risk of cardiovascular and oncological diseases, which increases proportionally to the number of years spent adopting out-of-phase rhythms.
According to a study conducted by the Massachusetts Institute of Technology (MIT). 23/10/2018
Melatonin against sleep disorders in patients with Alzheimer's
The main goal of the work is to generate new options to treat sleep disorders in patients with Alzheimer's, since many of the drugs that already exist interact negatively with the treatment, which patients with this disease, usually use to keep it under control .
Among the many complications these people suffer, which affects not only their quality of life, but also that of their family and those who are dedicated to taking care of them, are sleep disorders. In this context, a research group from the Ramˇn de la Fuente Mu˝iz National Institute of Psychiatry tests the effects of melatonin - the natural hormone that regulates the sleep cycle - in Alzheimer's patients. 06/10/2018
A research carried out dall'UBA (Buenos Aires University) shows that melatonin, the so-called sleep hormone, interrupts the normal development of Alzheimer's
Melatonin may serve to treat Alzheimer's. A search of the Laboratory of Neurosciences at the Faculty of 'Medicine UBA noted that the administration of melatonin interrupts the normal evolution of this neurological disease which begins with memory effects, a sense of orientation and produces a total aging
few years. "Melatonin does not cure Alzheimer's, but it has been proven to produce a significant reduction in the progression of the disease. Delaying the onset of more severe symptoms, such as the patient's uncontrollable shaking. It also increases the survival once diagnosed "revealed Daniel Cardinali, professor of physiology at the UBA.
The discovery of the interdisciplinary team of the Laboratory of Neuroscience Department of Physiology UBA work motivated to start other similar surveys in the United States, with a greater number of patients placed under observation. Currently he is conducting a study of patients treated in different medical centers specializing in Alzheimer's disease, under the supervision of the American Alzheimer's Association and another under the supervision of the National Institute of Health, which is being administered melatonin.
As explained Cardinals, the first indication of the possible benefits of melatonin in the treatment of patients with Alzheimer's disease a few years ago has been discovered, beginning with the case of two monozygotic twin brothers, in which the neurological disease was diagnosed with a difference of six months, possibly with hereditary origin, whereas the mother had suffered from the same disease.
"In one of the twins she was prescribed melatonin to treat sleep disturbances that occur during the illness progresses. The other not. The twin who was administered melatonin for 4 and a half years has not only improved his sleep problems, but it is able to live tuttogggi with his wife, which means that it is not entered in the advanced stage Alzheimer Dell'. On the contrary the other patient died five years after the appearance of the first symptoms of the disease, disease that has thus followed its normal evolution. "Said Cardinals, who has studied melatonin in the country since the introduction of commercial, in 1995 CONICET researcher and vice president of the Latin American Society of Sleep Medicine and the International Club of melatonin, based in Paris. "the case of the twins was an anecdotal fact, it suggested the possibility of a direct relationship between melatonin and Alzheimer's "said Cardinals. The first observations of the event were published in the Journal of Pineal Research in 1998.
Currently, the Laboratory of Neuroscience has under study more than 25 Alzheimer's patients treated with melatonin for five years. "Everyone has normalized sleep and have had a significant reduction in the progression of the disease," reported the Cardinals, highlighted by the Journal of Pineal Research as one of the three most productive researchers in the field of melatonin and the pineal gland.
Melatonin is secreted by the pineal gland, located at the center of the brain, is a hormone that regulates the biological clock of people. In other words, it is the substance that regulates sleep-wake cycle. "It has been assigned as can enhance sex life anti-aging and quality, but do not have a full scientific support. Melatonin is not a panacea for all (for example, is not suitable for young people), but now we are discovering its real effects, "he reported the Cardinals.
"It is estimated that after 60 years, two-thirds of people experience a significant decrease in the production of melatonin. In having a smaller quantity of melatonin, the elderly suffering from insomnia. With melatonin can catch up on sleep as individuals 40 years "she added the specialist. "In the slow sleep - that occurs at the beginning of the night when the peak is at about 3-4 am - are given the immune response, tissue recovery and memory consolidation" has detailed Cardinals. For this reason, it considers that the improvement of sleep problems in Alzheimer's patients, produces a significant reduction in the progression of the disease. 21/01/2017
Analgesic effects of MELATONIN
Interestingly, some experimental studies on animals demonstrate significant analgesic effects of employing melatonin. Moreover, clinical trials of experimental character on humans confirm the presence of significant analgesic effects also for humans.
Identified the effect of the tumor suppressor MELATONIN
The work, just published in the Journal of Pineal Research, was conducted by Rita Paroni and Michele Samaja group of Biochemistry, Department of Health Sciences of the University of Milan and Franco Fraschini of the Department of Medical Biotechnology and Medicine Translational the same State University in partnership with the University of Brescia and the University of Texas in San Antonio. 04/01/2016
MELATONIN: Damage of irregular shifts at work
This was revealed by a French study, published in the Journal of occupational medicine. The decline in persons who serve in times 'irregular' by at least 10 years is equivalent to six and a half years of natural aging